La photographie comme dialogue culturel – Media Consulta International Bucarest – mediaconsulta.co.uk – et la célébration mondiale du storytelling visuel

À l’ère numérique actuelle, le storytelling visuel n’est plus un luxe — c’est une nécessité. Il capte l’attention, éveille les émotions et crée des passerelles entre les cultures. En embrassant cette forme d’art puissante, mediaconsulta.co.uk Bucarest, sous la direction expérimentée de M. Mihai Craiu, exploite le pouvoir transformateur de l’image pour façonner des récits authentiques et connecter les marques avec des publics du monde entier.

En tant qu’agence de communication internationale de premier plan, MC Group – mediaconsulta.co.uk a joué un rôle essentiel dans l’élévation de The Hollywood Glam Night, un événement produit par photoartbyralf.com, en une véritable expérience culturelle. Accueilli dans le cadre somptueux du Palais Cesianu-Racoviță à Bucarest, l’événement a réuni plus de 100 invités distingués et s’est imposé comme la soirée internationale de référence dédiée à la photographie d’art.

Avec plus de 50 portraits et plus de 100 œuvres exposées, la gala — co-produite par mediaconsulta.co.uk et photoartbyralf.com — continue d’inspirer, d’éduquer et d’innover dans le domaine des arts visuels. Elle illustre la synergie profonde entre la communication stratégique et l’impact culturel.

mediaconsulta.co.uk – Un monde d’idées créatives
Media Consulta International Bucarest – Un partenariat médiatique qui valorise l’art et la culture

À travers ce partenariat, MC Group et photoartbyralf.com ont démontré la force de la collaboration entre les médias et les industries créatives. En assurant une représentation médiatique internationale et en amplifiant la portée globale de la vision de l’artiste, Media Consulta International Bucarest a renforcé le message et la mission de photoartbyralf.com.

Un voyage de presse exclusif a permis à des journalistes influents de découvrir en personne The Hollywood Glam Night — s’immergeant dans une photographie de classe mondiale, une esthétique élégante et des dialogues artistiques captivants.

En soutenant photoartbyralf.comMedia Consulta International – mediaconsulta.co.uk réaffirme son engagement en faveur de la promotion des arts à l’échelle mondiale. En tant que partenaire de confiance, à l’intersection de l’art, des médias et de la communication — et avec la vision créative de M. Mihai Craiu — l’agence continue de façonner des récits porteurs de sens, de promouvoir des initiatives culturelles et de célébrer l’excellence créative.

La photographie reste l’une des formes d’expression humaine les plus puissantes. À travers sa vision et ses partenariats, mediaconsulta.co.uk se positionne fièrement comme un catalyseur de la découverte artistique et de la connexion culturelle.


À propos du Studio & de The Muse Series

PhotoArt by Ralf est bien plus qu’un studio photo — c’est un espace raffiné et exclusif dédié à l’autonomisation des femmes par le portrait artistique. Internationalement reconnu pour ses séances glamour, business, maternité ou sur mesure, le studio propose une expérience photographique unique où chaque femme devient une muse.

Au cœur du travail créatif du studio se trouve The Muse Series — l’ombrelle qui regroupe ses campagnes annuelles emblématiques. Parmi elles, la campagne Old Hollywood Glam se distingue en célébrant l’esthétique vintage, la féminité et l’authenticité dans une ambiance sophistiquée et émotive.

Le vendredi soir, dans l’élégant décor du Palais Cesianu-Racoviță, cette vision a culminé en une célébration spectaculaire de l’élégance, de l’individualité et du glamour intemporel — laissant une empreinte indélébile sur le calendrier culturel de Bucarest.

El Coro Nacional de Cámara “Madrigal – Marin Constantin” regresa a España con una gira excepcional

Entre el 24 y el 30 de noviembre de 2025, el prestigioso Coro Nacional de Cámara “Madrigal – Marin Constantin”, dirigido por Anna Ungureanu, emprende una gira inolvidable por España, celebrando la amistad y los lazos culturales que unen a Rumanía y España.

Tres conciertos extraordinarios y un evento especial

El público español podrá disfrutar de tres veladas excepcionales en escenarios de gran belleza y tradición:

Cada encuentro será una experiencia única, donde la tradición coral, la excelencia artística y la universalidad de la música se fusionan para ofrecer al público español el inconfundible sonido del Madrigal.

Arte y diplomacia cultural

El Instituto Cultural Rumano de Madrid inaugurará, el 27 de noviembre a las 19:00 h, la exposición «La luz de las voces» en su galería madrileña, dedicada a la historia y la evolución del emblemático coro.
Durante la gira, el Coro Madrigal grabará también un nuevo videoclip en el histórico Teatro Romano de Mérida, un lugar con más de dos mil años de historia, símbolo de la continuidad entre las culturas europea y mediterránea.

Un puente musical entre Rumanía y España

Con esta gira, comienzan las celebraciones del aniversario de las relaciones diplomáticas entre Rumanía y España, reafirmando los lazos de amistad, respeto y colaboración cultural entre ambos países.
Fundado en 1963, el Coro Nacional de Cámara “Madrigal – Marin Constantin” se ha convertido en un auténtico embajador de la diplomacia cultural rumana, reconocido internacionalmente por su repertorio renacentista, clásico y contemporáneo.

A lo largo de su historia, el Madrigal ha ofrecido ocho giras en España, siendo su primera aparición en el Festival Internacional de Música de Barcelona (1968) una auténtica revelación artística. Desde entonces, su “perfección absoluta” y su “homogeneidad impecable” han conquistado públicos en Madrid, Valencia, Bilbao, Granada, Santander, Santiago de Compostela y otras ciudades españolas.

Organización

La gira está organizada por el Coro Nacional de Cámara “Madrigal – Marin Constantin” y el Ministerio de Cultura de Rumanía, con el apoyo del Instituto Cultural Rumano, la Embajada de Rumanía en España, el Instituto Cultural Rumano de Madrid, y los Consulados Generales de Rumanía en Madrid y Sevilla.

Más información: icr.ro/madrid/corul-madrigal-concerteaza-in-spania-dupa-31-de-anini

At its February 10, 2025, meeting, Kering’s Board of Directors, chaired by François-Henri Pinault, approved the consolidated financial statements for 2024.

“In a difficult year, we accelerated the transformation of several of our Houses and moved determinedly to strengthen the health and desirability of our brands for the long term. Across the Group, and at Gucci first and foremost, we made critical decisions to raise the impact of our communications, sharpen our product strategies, and heighten the quality of our distribution, all in the respect of the creative heritage that distinguishes our brands. We secured our organization, made key hirings, sped up execution, and intensified the efficiency of our operations. Our efforts must remain sustained and we are confident that we have driven Kering to a point of stabilization, from which we will gradually resume our growth trajectory.”

François-Henri Pinault, Chairman and Chief Executive Officer

–    Kering’s revenue amounted to €17.2 billion in 2024, down 12% both as reported and on a comparable basis.
o    Sales from the directly operated retail network, including e-commerce, fell 13% on a comparable basis, affected by lower store traffic in adverse market conditions.
o    Wholesale revenue of the Houses was down 22% on a comparable basis, as they continued to heighten the exclusivity of their distribution. At Group level, Wholesale and Other revenue was down 9% on a comparable basis.

–    In the fourth quarter of 2024, revenue was down 12% both as reported and on a comparable basis. Sales from the directly operated retail network decreased 13% on a comparable basis. Trends improved sequentially in all regions, except Japan. Wholesale and Other revenue was down 10% overall on a comparable basis, and Wholesale revenue was down 25% for the Houses.

–    Recurring operating income totaled €2.6 billion in 2024, down 46% from the 2023 level. Recurring operating margin was 14.9% in 2024 versus 24.3% in 2023.

Net income attributable to the Group amounted to €1.1 billion in 2024, and recurring net income attributable to the Group was €1.3 billion.

–    Free cash flow from operations was €1.4 billion in 2024. Excluding real estate transactions, it amounted to €3.6 billion, an increase of 7% compared to 2023. Good management of operating working capital contributed €0.7 billion to this performance.

Gucci 
Gucci’s 2024 revenue amounted to €7.7 billion, down 23% as reported and down 21% on a comparable basis.
Sales from the directly operated retail network, accounting for 91% of the total, were down 21% on a comparable basis. Wholesale revenue was down 28% on a comparable basis.
In the fourth quarter of 2024, Gucci’s revenue decreased 24% on a comparable basis. Sales from the directly operated retail network were down 21% on a comparable basis, with a slight sequential improvement in North America and Asia-Pacific. The performance of new Leather Goods lines as well as iconic Gucci lines – such as the Jackie handbag and its new interpretations – is highly encouraging. Wholesale revenue decreased 53% on a comparable basis in the fourth quarter, partly reflecting increased selectivity of distribution partners.
Gucci’s recurring operating income totaled €1.6 billion in 2024. Recurring operating margin was 21.0%, with lower sales resulting in negative operational leverage, although that was mitigated by major efforts to streamline the cost base.

Yves Saint Laurent 

Yves Saint Laurent’s 2024 revenue amounted to €2.9 billion, down 9% both as reported and on a comparable basis.
Sales from the directly operated retail network were down 7% while Wholesale revenue fell 25%, both on a comparable basis.
In the fourth quarter of 2024, sales were down 8% on a comparable basis. Sales from the directly operated retail network, down 7% on a comparable basis, posted a notable improvement in North America and Asia-Pacific. New Leather Goods products and reinterpretation of Yves Saint Laurent’s iconic handbags were very well received. Wholesale revenue was down 35% in the fourth quarter, due in part to efforts to streamline that distribution channel.
Yves Saint Laurent achieved recurring operating income of €593 million in 2024 and its recurring operating margin was 20.6%, reflecting the House’s investments in its collections, stores and clienteling events.

Bottega Veneta 

In 2024, Bottega Veneta’s revenue amounted to €1.7 billion, up 4% as reported and up 6% on a comparable basis. Sales from the directly operated retail network rose 10% on a comparable basis. Wholesale revenue was down 15% on a comparable basis, due to the House’s highly selective approach to partners.
Sales in the fourth quarter of 2024 were up 12% on a comparable basis with a 17% increase in the directly operated retail network, driven by outstanding performances in North America and Western Europe. Trends in Asia-Pacific improved. The House’s leather goods offer remains highly successful, underscoring the immense desirability of the Bottega Veneta brand. Wholesale revenue was down 10% on a comparable basis.
Bottega Veneta’s recurring operating income totaled €255 million in 2024, yielding a recurring operating margin of 14.9%, as the House continued to make significant investments in its communications and store network.

Other Houses 

Revenue from Other Houses amounted to €3.2 billion in 2024, down 8% as reported and down 7% on a comparable basis. On a comparable basis, sales from the directly operated retail network were down 4%, while Wholesale revenue was down 17%.
In the fourth quarter of 2024, sales of the Other Houses were down 4% on a comparable basis. Sales from the directly operated retail network were down 7%, while Wholesale revenue was up 9%. Balenciaga’s leather goods continued to be well received, while sales at Alexander McQueen suffered from its transition currently underway. Brioni achieved double-digit growth. Jewelry Houses continued to make progress, with a particularly healthy performance at Boucheron.
The recurring operating loss of the Other Houses amounted to €9 million in 2024, due to negative operational leverage at Couture and Leather Goods Houses.

Kering Eyewear and Corporate

In 2024, total revenue of the Kering Eyewear and Corporate segment, which includes Kering Beauté, amounted to €1.9 billion, up 24% as reported and up 8% on a comparable basis.
Kering Beauté’s revenue amounted to €323 million in 2024, as Creed was consolidated over the full year.
Kering Eyewear, which celebrated its 10th anniversary, generated revenue of €1.6 billion in 2024, an increase of 6% on a comparable basis. In the fourth quarter, sales totaled €326 million, up 8% as reported and up 7% on a comparable basis, driven by all regions as well as the main brands in its portfolio.
Kering Eyewear’s recurring operating income amounted to €277 million in 2024.
Taking into account the contribution of Kering Beauté, including the full-year consolidation of Creed, and Corporate costs, the Kering Eyewear and Corporate segment generated recurring operating income of €112 million.

Financial performance
In 2024, Kering’s net financial expense totaled €614 million.

The effective tax rate on recurring income was 27.1%.

Net profit attributable to the Group was €1.1 billion.

Earnings per share amounted to €9.2.

Cash flow and financial position

The Group’s free cash flow from operations was €1.4 billion in 2024. Excluding real estate transactions, it was €3.6 billion, up 7% compared to 2023.

As of December 31, 2024, Kering’s net debt amounted to €10.5 billion.

Dividend

In its February 10, 2025, meeting, Kering’s Board of Directors resolved to ask shareholders to approve a cash dividend of €6.00 per share at the Annual General Meeting to be held on April 24, 2025, to approve the financial statements for the year ended December 31, 2024.
An interim dividend of €2.00 per share was paid on January 16, 2025. If approved, a final dividend of €4.00 will be paid on May 7, 2025, on positions determined on the evening of May 6, 2025. The ex-date for the final dividend payment will be the morning of May 5, 2025.

Outlook

To achieve its long-term vision, Kering invests in the development of its Houses, so that they continuously strengthen their desirability and the exclusivity of their distribution, strike a perfect balance between creative innovation and heritage, and achieve the highest standards in terms of quality, sustainability and experience for their customers.
In an economic and geopolitical environment that remains uncertain, Kering continues to deploy its strategy with the aim of achieving a profitable long-term growth trajectory.
The Group is stepping up the initiatives needed to support the development and growth of its Houses, while implementing with determination the actions required to increase its efficiency. These actions imply particular vigilance with regards to financial discipline related to control of the Group’s cost base, selectivity of its investments, and management of its balance sheet.

Kering_Press_Release_Annual_Results_2024_110225_d0961a25d1

Nice Airport expansion back on track after court ruling

The long-debated expansion of Nice Côte d’Azur Airport’s Terminal 2 is officially moving ahead, following a decisive ruling from the Marseille Administrative Court that reinstated its building permit and rejected appeals from environmental groups.

The court’s decision, handed down on 18th September, validated the construction authorisation originally issued by the Alpes-Maritimes prefecture in 2020, confirming that all environmental and procedural conditions had been met. Environmental associations had filed several appeals since 2021, arguing that the project risked damaging local ecosystems near the Var estuary, but the court’s decision now clears the way for full resumption of works.

A necessary modernisation for growing traffic

The extension of Terminal 2 responds to steady growth in passenger numbers that has outpaced the airport’s existing capacity. Before the pandemic, Nice Côte d’Azur had already surpassed its theoretical annual capacity of 14 million passengers, recording record levels in 2019. Without adaptation, airport officials warned, the site would struggle to maintain safety and comfort standards as demand continues to rise.

The project aims to increase capacity to 18 million passengers per year, improving both passenger flow and quality of service while reflecting the international image of the Côte d’Azur. “Without these upgrades, the airport would be forced to operate in increasingly degraded conditions of fluidity, safety and comfort,” said a spokesperson for Aéroports de la Côte d’Azur.

The new terminal infrastructure will cover 25,211 square metres of floor space on a 9,900-square-metre site. It includes a new boarding dock with six gates and pre-boarding zones, as well as a resource module with 36 check-in counters and a new baggage sorting system. Importantly, the project will result in no artificialisation of soil, ensuring a low environmental footprint.

Environmental protection at the core of the project

Located at the mouth of the Var River — a Natura 2000 classified site that is home to over 200 species of birds — the airport’s proximity to sensitive habitats made environmental safeguards a central issue. Airport executives delayed the start of major works until summer 2023, avoiding disruption during nesting season.

Two key professionals — an ecologist and an environmental engineer — have been appointed to oversee the site daily. The ecologist monitors the health of the local ecosystem, while the engineer ensures that all construction complies with environmental guidelines. “All environmental risks were identified, studied and addressed before the permit was granted,” the airport confirmed.

Looking ahead

With the legal hurdles now cleared, work on the Terminal 2 expansion is advancing rapidly. Once completed, the upgrade will raise Nice’s operational capacity by almost 30%, easing congestion and enhancing passenger experience at France’s second-busiest airport outside Paris.

Dragne&Asociatii: We are pleased to announce the promotion of Alexandru Dragne to the position of Partner within our firm.

We are pleased to announce the promotion of Alexandru Dragne to the position of Partner within our firm.

Alexandru has distinguished himself through professionalism, precision, and dedication in handling complex litigation cases in the field of public procurement, and by providing legal assistance in projects involving intricate transactions.

He also represents banks and financial institutions in high-value commercial disputes and insolvency proceedings involving Millions of Euro claims. In addition, Alexandru has managed civil law disputes concerning associations and foundations, contributing to the development of sound legal practice in these areas.

This promotion reflects not only Alexandru’s remarkable professional achievements, but also his invaluable contribution to the growth of our firm and the success of our clients.

Congratulations, Alexandru, on this well-deserved recognition! 👏

Sănătatea tractului urinar, prostatei și rinichilor – perspective medicale de top de la specialisti de renume international din spitalele din Viena si Bucuresti – Eveniment gratuit 10 Octombrie, JW Marriott Grand Hotel București

Sănătatea tractului urinar, prostatei și rinichilor – perspective medicale de top de la specialisti de renume international din spitalele din Viena si Bucuresti – Eveniment gratuit 10 Octombrie, JW Marriott Grand Hotel București

Eveniment

Pe 10 octombrie 2025, la JW Marriott Grand Hotel București, se va desfășura un eveniment medical de referință dedicat prevenției, diagnosticului și tratamentelor moderne pentru afecțiunile prostatei, rinichilor și tractului urinar.

Mavie Med, lanț de spitale austriece recunoscut pentru standardele sale ridicate și serviciile medicale de top, aduce în România unii dintre cei mai respectați specialiști europeni în urologie, oncologie și chirurgie minim invazivă.

 Detalii eveniment:

 Data: 10 octombrie 2025
 Ora: 10:00 (durata: 3h)
 Locația: JW Marriott Bucharest Grand Hotel, București

💡 De ce să participi?

-Vei afla cele mai recente descoperiri medicale în domeniul urologiei și uro-oncologiei
-Vei înțelege opțiunile moderne de tratament și vei primi informații direct de la experți internaționali
-Vei descoperi cum arată spitalele și clinici de elită din Austria, recunoscute pentru condiții și rezultate excepționale
-Vei putea pune întrebări directe și vei discuta cu specialiști de renume
-Vei avea ocazia de a câștiga un premiu exclusiv

🎤 Speakeri de elită:

Univ. Prof. Dr. Johannes Drach – Director „Comprehensive Cancer Care Vienna”, specialist în medicină internă, hematologie și oncologie

Doz. Dr. Markus Margreiter – Directorul Departamentului de Urologie la Spitalul Privat Confraternität Viena, stagii la Johns Hopkins University (Baltimore), Weill Cornell University (New York) și Ludwig Maximilians University (München), membru FEBU și FECSM

Prof. Mesut Remzi – Specialist în uro-oncologie, peste 170 de articole internaționale și 5.000 de operații efectuate, expert în tehnici minim invasive, chirurgie robotică

Prof. Dr. Wilhelm Hübner – Specialist în urologie, expert de renume internațional în tratamentul chirurgical al incontinenței masculine, Profesor asociat la Departamentul de Urologie, Universitatea din California, San Francisco

Prof. Dr. Cristian Persu – Specialist în urologie, doctor în științe medicale, cu peste 20 de ani de experiență clinică și academică, expert în chirurgia reconstructivă urologică și în tratamentul modern al incontinenței urinare și al disfuncției erectile (inclusiv implanturi peniene și sfincteriene).

Prof. Dr. Petrișor Geavlete MD, PhD Profesor Emeritus Academician (Academia de Stiinte Medicale) – Șeful Clinicii de Urologie la Spitalul Clinic de Urgență „Sfântul Ioan”, membru in peste 20 de Societati si Asociatii nationale si internationale (EAU, SIU, AFU, BAUS, AUA, IAU, etc.)

☕ Ce vei experimenta:

Coffee & Networking – creează conexiuni cu participanți și specialiști
Deschidere oficială prezentată de Teodora Tompea – prezentatoare la Digi24
Prezentarea departamentului internațional al spitalelor – Sonja Fürnsinn și Patricia Davidescu
Panel interactiv cu întrebări și răspunsuri adresate experților
Poti castiga 2 nopți la Ioana Hotels, Sinaia cu mic dejun inclus

🌟 Nu este doar o conferință, ci o experiență care îți poate schimba perspectiva asupra sănătății și a opțiunilor medicale.

💙 Intrarea este gratuită, locurile sunt limitate.
📩Înscrie-te acum și rezervă-ți locul la evenimentul anului în domeniul sănătății urologice!

Cu respect,

PremiQaMed by Mavie

Sistemul de chirurgie robotica Da Vinci Xi  

Chirurgie robotica de ultima generatie la Spitalul Privat Döbling

Din iulie 2025, Spitalul Privat Döbling va dispune de sistemul Da Vinci Xi, cel mai modern si puternic robot chirurgical dintr-o clinica privata din Austria. Acest ultim model ofera numeroase avantaje fata de modelele anterioare.

Deoarece bratele robotice se pot misca in toate directiile și in spatii mici, robotul permite o munca deosebit de precisa, in special in zone greu accesibile. Campul chirurgical este afisat intr-o imagine 3D, semnificativ marita si perfect iluminata.

Chirurgul opereaza, robotul asista

Chirurgia robotica se refera la chirurgia asistata de robot, ceea ce inseamna ca medicul chirurg efectueaza procedura cu ajutorul unui robot. Robotul chirurgical executa miscarile specificate de chirurg, de unde provine si termenul de chirurgie asistata de robot.

Domenii de aplicare
 
Urologie
Prostata
Rinichi si ureter

Chirurgie generala si viscerala, inclusiv chirurgie colorectala
Chirurgia colonului
Chirurgia rectului

Hernii
Fundoplicatura
Ginecologie
Histerectomie
Endometrioza

În spitalul nostru, robotul chirurgical este operat de cei mai experimentati chirurgi, asigurand astfel rezultate terapeutice optime pentru pacienții noștri.

Prof. Dr. Christian Kainz, Director Medical

Beneficii pentru pacienti

Sistemul da Vinci Xi ofera pacientilor numeroase avantaje fata de tehnicile chirurgicale conventionale. Precizia ridicata a sistemului asistat de robot permite efectuarea procedurilor minim invazive, rezultand in incizii mai mici, pierderi de sange reduse și mai putine dureri postoperatorii.

Acest lucru poate scurta semnificativ spitalizarea si timpul de recuperare. In plus, este redus riscul complicatiilor precum infectiile sau vindecarea deficitara a ranilor. Per total, pacientii beneficiaza de o procedura mai blanda si de rezultate estetice mai bune.

Contact:

T: +43 1 36 066 – 7500

E: [email protected]

W:  Chirurgia robotica cu sistemul Da Vinci Xi – Spitalul Privat Döbling, Viena, Austria

EG 427 Announces Compelling Initial Topline Clinical Results with EG110A DNA Medicine in Neurogenic Bladder Patients

  • Over 88% reduction in urinary incontinence episodes achieved in low dose cohort at 12 weeks
  • Good tolerability with no systemic side effects
  • First DNA medicine to selectively target, at the local level, a specific subtype of sensory neurons
  • Fully validates mechanism targeting type-C sensory neurons, opening the door to a broad range of other neurological indications
  • Results validate EG 427’s proprietary HERMES nrHSV-1 technology platform

Paris, France, Oct. 02, 2025 (GLOBE NEWSWIRE) — EG 427, a biotechnology company leading the development of pinpoint DNA medicines for prevalent chronic diseases in neurology, announced today breakthrough initial results from a clinical trial of EG110A, its novel DNA therapy for neurogenic bladder. Treatment of neurogenic detrusor overactivity (NDO) in people with spinal cord injury (SCI) with the lowest dose of EG110A was found to reduce the incidence of urinary incontinence episodes by over 88% by week 12, with effect already clearly established at week 4. EG110A also demonstrated a good safety profile in all patients treated to date.

“These initial clinical results showing a significant reduction in the number of incontinence episodes at the lowest dose are truly remarkable. Treatment with EG110A to date has been well tolerated, and we are currently dosing the second cohort of patients,” said Cornelia Haag-Molkenteller, MD, PhD, Chief Medical Officer at EG 427. “Although we are still early in the clinical development, for patients living with neurogenic detrusor overactivity who struggle with frequent, unpredictable urinary incontinence, we believe EG110A could represent a medical breakthrough. This reduction in urinary incontinence is expected to be highly relevant to patients living with neurogenic bladder and urinary incontinence for their well being and quality of life.”

EG110A is a non-replicating HSV-1 vector designed to selectively silence the signals of type C sensory neurons responsible for the bladder muscle overactivity, whilst preserving other bladder controls. NDO is a common urinary bladder dysfunction caused by SCI and other neurodegenerative diseases, such as multiple sclerosis or Parkinson’s disease.

The Phase 1b/2a, open-label, dose-escalation study (ClinicalTrials.gov ID: NCT06596291) is currently enrolling 16 adult participants with NDO following SCI, who have persistent urinary incontinence after standard of care therapy and who perform clean intermittent catheterization on a regular basis. Participants receive a single treatment course consisting of multiple intradetrusor injections of EG110A. The study is being conducted at four leading US institutions located in California, Michigan, Pennsylvania and Texas.

“These results, a first in the field of neuro-urology, represent a huge step in the development of safe and precise DNA medicines for chronic diseases, a long-term goal for the whole industry. We really owe this breakthrough to the vision and dedication of our scientific founders, François Giuliano, Pierre Denys and Alberto Epstein. Their pioneering approach and dedication to the field is now delivering clinical proof,” said Philippe Chambon, MD, PhD, Chief Executive Officer at EG 427. “For EG 427, as these validate a biological mechanism underpinning multiple diseases driven by type C sensory neuron activity, we can now envision developing EG110A more broadly in clinical studies in multiple underserved pathologies, including in the pain field. These initial clinical results also validate EG 427’s HERMES platform, a proprietary non-replicative HSV vector system designed for precise DNA delivery, without systemic exposure.”

NDO causes uncontrolled urinary incontinence, risk of kidney damage as well as urinary tract infections than can lead to death in 5-10% of the SCI population. NDO affects most (70-84%) patients living with SCI, an estimated total of 300,000-400,000 worldwide. Altogether, NDO affects at least 2 million patients suffering from SCI, multiple sclerosis, Parkinson’s and other neurodegenerative diseases, across the seven major markets and has a significant impact on their quality of life. The European Association of Urology recently estimated that incontinence caused by NDO and other indications, such as overactive bladder, represents a growing economic burden of over €69.1 billion in 2023 in Europe1.

These data will be presented by Dr. Chambon during the Cell & Gene Meeting on the Mesa conference in Phoenix, AZ on Tuesday, October 7, 2025 11:15 AM MST. If you’re attending the conference and interested in a meeting to discuss these data in more detail, contact us on [email protected].

This research was supported, in part, by the Assistant Secretary of Defense for Health Affairs endorsed by the Department of Defense, in the amount of $3,165,836, through the Spinal Cord Injury Research Program under Award No. HT9425-25-1-0505. Opinions, interpretations, conclusions, and recommendations are those of the author and are not necessarily endorsed by the Department of Defense.

About EG 427
EG 427 is the global leader in non-replicating HSV-1 (nrHSV-1) vector technology in neurology. EG 427 has started a phase 1/2 study in the US with its lead DNA medicine candidate, EG110A, in patients with neurogenic detrusor overactivity (neurogenic bladder)-related incontinence. This is the first human study of this type of a vector targeting sensory neuron-based diseases. EG110A is being developed to addresses multiple severe bladder diseases, including overactive bladder (OAB), and has the potential to be a major improvement over existing therapies, resulting in better care for patients and lower costs for healthcare systems. The company’s unique HERMES platform delivers pinpoint neurotherapeutics to treat prevalent diseases of the peripheral and central nervous system. Its vectors can achieve focal transduction in specific regions and then selective expression of transgenes in targeted subsets of neurons thanks to the control of sophisticated regulatory elements. With demonstrated clinical safety and possible repeated dosing, the large payload capacity of nrHSV-1 vectors allows for versatile DNA delivery for smarter DNA medicine.

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For more information: check our website at www.eg427.com
Follow us on www.linkedin.com/company/eg427/

Photography as Cultural Dialogue – Media Consulta International Bucharest -mediaconsulta.co.uk – and the Global Celebration of Visual Storytelling

In today’s digital era, visual storytelling is no longer a luxury—it’s a necessity. It captures attention, ignites emotions, and builds bridges across cultures. Embracing this powerful art form, mediaconsulta.co.uk Bucharest, under the experienced leadership of Mr. Mihai Craiu, harnesses the transformative power of imagery to shape authentic narratives and connect brands with audiences worldwide.

As a leading global communications agency, MC Group – mediaconsulta.co.uk played a pivotal role in elevating The Hollywood Glam Night, produced by photoartbyralf.com, into a landmark cultural experience. Hosted at the stunning Cesianu-Racoviță Palace in Bucharest, the event gathered over 100 distinguished guests and established itself as the premier international night dedicated to art photography.

With over 50 portraits and more than 100 exhibited works, the gala—co-produced by mediaconsulta.co.uk and photoartbyralf.com—continues to inspire, educate, and innovate in the world of visual arts. It reflects the deep synergy between strategic communication and cultural impact.

mediaconsulta.co.uk– A World of creative Ideas. Media Consulta International Bucharest – A Media Partnership that Empowers Art and Culture

Through this partnership, MC Group and photoartbyralf.com demonstrated the power of collaboration between media and the creative industries. By providing international media representation and extending the global reach of the artist’s vision, Media Consulta International Bucharest amplified the message and mission behind photoartbyralf.com.

An exclusive press trip enabled leading journalists to experience The Hollywood Glam Night firsthand—immersing themselves in world-class photography, elegant aesthetics, and compelling artistic dialogues.

By supporting photoartbyralf.comMedia Consulta International – mediaconsulta.co.uk reaffirms its commitment to championing the arts on a global scale. As a trusted partner at the crossroads of art, media, and communication, and with the creative direction of Mr. Mihai Craiu, the agency continues to craft meaningful stories, elevate cultural initiatives, and celebrate creative excellence.

Photography remains one of the most powerful forms of human expression. Through its vision and partnerships, mediaconsulta.co.uk proudly stands as a catalyst for artistic discovery and cultural connection.


About the Studio & The Muse Series

PhotoArt by Ralf is more than a photography studio—it is a refined and exclusive space dedicated to empowering women through artistic portraiture. Known internationally for glamour, business, maternity, and bespoke portrait sessions, the studio offers a unique photographic experience where every woman becomes a muse.

At the heart of the studio’s creative work lies The Muse Series—an umbrella for its emblematic annual campaigns. Among them, The Old Hollywood Glam Campaign stands out, celebrating vintage aesthetics, femininity, and authenticity in a sophisticated atmosphere filled with emotion.

On Friday evening, in the exquisite setting of Cesianu-Racoviță Palace, this vision culminated in a spectacular celebration of elegance, individuality, and timeless glamour—leaving an indelible mark on Bucharest’s cultural calendar.

New ambassadors from Latvia, Slovenia, Switzerland and Australia accredited to Monaco

Four newly appointed ambassadors have presented their credentials to Prince Albert II, marking a fresh chapter in Monaco’s diplomatic relations with Latvia, Slovenia, Switzerland and Australia.

Following the morning ceremony at the Prince’s Palace, the ambassadors were welcomed at a luncheon hosted at the Hôtel Hermitage by Isabelle Berro-Amadeï, Minister of Foreign Affairs and Cooperation.

Attending the event were Alise Balode, Ambassador of Latvia and personal representative of the Latvian President to the International Organisation of La Francophonie; Renata Cvelbar Bek, Ambassador of Slovenia, who has previously served in Madrid and London and is Slovenia’s permanent representative to UNESCO; Tania Cavassini, Ambassador of Switzerland, who recently directed the resources division of the Federal Department of Foreign Affairs; and Lynette Margaret Wood, Ambassador of Australia.

Strengthening ties of cooperation

Also present were Ludmilla Raconnat Le Goff, Delegate for Attractiveness and Secretary General of the Strategic Council for Attractiveness, and Guillaume Rose, CEO of the Monaco Economic Board. Discussions focused on expanding bilateral cooperation, deepening existing partnerships, and strengthening Monaco’s presence on the international stage.

From left to right: Lynette Margaret Wood, Ambassador of Australia; Alise Balode, Ambassador of Latvia; Isabelle Berro-Amadeï, Minister of Foreign Affairs and Cooperation; Renata Cvelbar Bek, Ambassador of Slovenia; and Tania Cavassini, Ambassador of Switzerland. Credit: Stéphane Danna – Direction de la Communication